Nation
US Govt Begins New €22.8m Lassa Vaccine Trial In Nigeria
The International AIDS Vaccine Initiative (IAVI) was awarded €22.8million by the European & Developing Countries Clinical Trials Partnership and the Coalition for Epidemic Preparedness Innovations (CEPI) to conduct a Phase IIb clinical trial of IAVI’s Lassa fever vaccine candidate among adults and children in Liberia, Nigeria, and Sierra Leone.
The vaccine candidate uses a recombinant vesicular stomatitis virus vector, which is now registered for use in eight African countries.
A statement by the US Mission in Nigeria, made available to The Tide via email, said, “This joint award supports an international collaboration across Africa, Europe, and North America, called the ‘Lassa Fever Vaccine Efficacy and Prevention for West Africa’ (LEAP4WA), which will also strengthen the research capacity of investigational sites where Lassa fever outbreaks and disease occur frequently.
“The LEAP4WA consortium consists of the following members: IAVI Inc., U.S.; IAVI Stichting, Netherlands; Tulane University School of Public Health and Tropical Medicine, U.S.; Ministry of Health and Sanitation/Kenema Government Hospital in Sierra Leone; Imperial College of Science Technology and Medicine, U.K.; University of Liberia, Liberia; Epicentre, France; and Henry M. Jackson Foundation Medical Research International Ltd/Gte (HJFMRI), Nigeria.
“In Nigeria, HJFMRI will conduct the study at its Clinical Research Center (CRC) supported by the Walter Reed Army Institute of Research.
“Other supported WRAIR Lassa projects being implemented at the CRC and other sites across Nigeria include a Lassa incidence study in collaboration with the African Centre of Excellence for Genomics of Infectious Diseases (ACEGID), a Lassa seroprevalence study, and a potential opportunity for a CEPI-funded Phase IIa Lassa vaccine study through a WRAIR/IAVI collaboration.
“When infected with Lassa fever virus, patients exhibit a high fever accompanied by bleeding, sore throat, vomiting, and body pains.
“The zoonotic virus, which rapidly spreads through bodily fluids, is transmitted to man by an infected multi-mammate rat, (mastomys natalensis).
“The illness was first reported in the Lassa community in Borno State, Nigeria, when two missionary nurses died from an unusual febrile illness.
“Since then, outbreaks continue to be reported in Nigeria and the disease, which is gradually becoming endemic in many parts of West Africa is now being transported to overseas country like the US and UK.
“Despite these outbreaks, there is yet no Lassa fever vaccine.
“An estimated 300,000 to 500,000 Lassa fever cases are diagnosed annually, resulting in approximately 5,000 deaths.
“The World Health Organization has identified Lassa fever as one of the top emerging pathogens likely to cause severe outbreaks in the near future.
“In 2018, the Nigeria Centre for Disease Control (NCDC) reported the largest ever number of cases in Nigeria, with over 600 confirmed cases and over 170 deaths.
“As of May, 2021, 14 states have recorded at least one confirmed case and over 2000 suspected cases this year, with the majority of cases emanating from Edo and Ondo states.
“CRC was established in 2014, initially supporting Phase II Ebola vaccine trials funded by Glaxo Smith Kline and Janssen.
“Since that time, its rapidly expanding research efforts have covered a broad range of infectious diseases. Of note, current research also includes two Covid-19 studies. Site preparations are ongoing for an imminent Phase III SARS-CoV-2 candidate vaccine trial sponsored by Sanofi Pasteur.
“Under a collaborative grant application between HJFMRI and ACEGID, the CRC was selected for an Africa Centre for Disease Control grant to potentially conduct a study entitled “Assessing the Effect of SARS-CoV-2 Variants on Vaccine-induced and Naturally-acquired Immune Responses in Nigeria” (SARS-CoVAN Project), the statement added.
Nation
Cleric Preaches Love As Deputy Governor, Chief Judge Grace Wedding In PH
The Presiding Bishop of Kingdom Life Gospel Ministries Outreach, Port Harcourt, Bishop Victor Uzosike, has described love as the bedrock of human existence, family stability and societal harmony, stressing that without love, nothing meaningful can thrive.
Bishop Uzosike made this assertion while speaking to journalists during the wedding ceremony of his daughter, Praise Uzosike, to Architect Chibuzor Akubueze on Saturday, December 20, 2025. The solemnisation was held at the Kingdom Life Gospel Ministries Outreach, Port Harcourt, and was attended by dignitaries from across Nigeria and beyond.
According to the cleric, love is not only the foundation of relationships but also a powerful force that determines the success of individuals, families and communities.
“If you do not love a place, that place will not bless you. If you do not love your children, they will not be useful to you. If you do not love your family, your family will become a strange island to you. What you do not love, you do not have. Love is the key,” he said.
Reflecting on his family’s journey, Bishop Uzosike said God’s love had sustained them through seasons of challenges and triumphs, noting that unity had remained their greatest strength.
“We have stayed together as one family. God has shown us love in miraculous and mysterious ways, especially during difficult times,” he stated.
Describing the wedding as an amazing and beautiful experience, the bishop expressed appreciation for the show of love from his daughter’s friends, many of whom travelled from the United Kingdom and Ghana to attend the ceremony. He revealed that some of them personally paid for their flights and accommodation, which he described as a rare display of genuine friendship.
He also disclosed that his first daughter, who lives in Manchester, United Kingdom, with her husband, could not attend the wedding due to tight schedules, but noted that she remains happily married and fulfilled.
While thanking guests for honouring his family with their presence, prayers and goodwill, Bishop Uzosike said he felt proud and grateful to God.
“One of the greatest gifts God can give to a man is children who are sound in all ramifications. My children can see, hear, speak and walk. That alone is enough reason to be grateful,” he said.
He praised the bride, describing Praise as an exceptional achiever who had distinguished herself academically. According to him, she completed secondary school at 15, graduated with First Class honours at 19, and earned distinctions in her MBA as well as her first and second master’s degrees.
“For a long time, people believed that highly educated women may not marry early or at all. Today, Praise has proved otherwise. She has made her mother and me very proud,” he said, describing her as a rare gem.
Bishop Uzosike also expressed joy over his son-in-law, whom he described as God-fearing, disciplined and professionally sound.
“He is well brought up, passionate about God and morally upright. His parents did a great job. My wife, Pastor Esther, also did an excellent job,” he added.
The wedding ceremony attracted prominent personalities, including the Deputy Governor of Rivers State, Prof. Ngozi Odu; the Chief Judge of Bayelsa State, Justice Matilda Ayemeyie; and several senior clerics.
Bishop Fidelis Ugbong officiated the solemnisation, while Apostle Chika Onuzo delivered the sermon, identifying communication, sex and money as key factors that can strengthen or weaken marriages.
Prof. Ngozi Odu also prayed for the couple and paid glowing tributes, drawing admiration from attendees.
The reception, held at the Golden Tulip Hotel, Port Harcourt, was equally colourful. Justice Matilda Ayemeyie proposed the toast, describing marriage as not always a bed of roses and emphasising patience, commitment and understanding.
The event was chaired by Chief Henry Nwabugo and attended by notable personalities, including retired Supreme Court Justice Mary Odili; Apostle David Zilly-Aggrey; Hon. Otunba Jumbo; Nze Best Anele; and Prof. Henry Ogiri, among others.
Guests were entertained with dance performances by the couple, while the parents’ outing added elegance to the celebration. The master of ceremonies, Ambassador Kingsley, kept the audience engaged with humour and interactive sessions.
Overall, the wedding was a remarkable blend of spirituality, culture and celebration, marked by love, joy and unforgettable moments.
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