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Ewedu Leaf Effective Against Ulcer – Study

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If you’ve ever tried the delicious slimy soup called ‘ewedu’ in Yoruba or ‘rama’ in Hausa, you know how slimy it is. Now, this slimy soup can be used as an alternative therapy for the relief of stomach pain and ulcers.
Scientists in a study of Corchorus olitorius leaf, what is commonly called jute leaf, evaluated its effects on the passageway of the digestive system that leads from the mouth to the anus, on the diclofenac-induced gastric ulcers.
In the study, the researchers found that Corchorus trilocularis leaf extract has gastro-protective effects against diclofenac-induced gastric ulcers and attributed this effect to its inhibition of gastric acid secretion through multiple pathways in a dose-dependent fashion.
It prevents the digestive juice from attacking the wall of the stomach, preserves the mediation, increases the stomach’s pH and inhibits gastric acid secretion.
For the study, 36 Sprague dawley rats of either sex weighing 150-200 grams were randomly assigned into a normal control (distilled water), negative control (distilled water plus diclofenac sodium), treatment (200 and 400 mg/kg Corchorus trilocularis Linn plus diclofenac sodium), positive control group (omeprazole plus diclofenac sodium), or comparison group (400 mg/kg aqueous leaf extract of spinach).
In the study, Corchorus trilocularis extract significantly reduced the ulcer index and total acidity in comparison to the diclofenac group. The high dose extract also increased the alkaline nature of the stomach while also protecting the cells of the stomach. However, it did not significantly affect the volume of gastric secretions.
The researchers in the journal, Discovery Phytomedicine, declared “the findings in this study support the use of Corchorus trilocularis Linn by some communities in Eastern Africa for the relief of stomach pain and ulcers.
“In addition, it provides a novel finding that encourages its use as alternative therapy for those with pre-existing gastric ulcers, with the preferred consumption in its original state as a vegetable.”
One of the aggressive factors for gastric ulcer is the unending or high dose usage of Non-Steroidal Anti-Inflammatory Drugs (NSAIDs), which are among the most commonly used drugs worldwide. NSAIDs such as diclofenac usually used to relieve swelling and pain associated with conditions like gout, migraine and rheumatoid disease are commonly associated with the development of gastric ulcers.
Despite progress in the production of effective therapies against gastric ulcers, herbs and vegetables still provide an important source of alternative therapy in the prevention of ulcers.
Corchorus trilocularis, which is consumed as green leafy vegetables that are boiled and used as relish or potherb, is used for treatment of diseases of the abdominal organs and seeds for the treatment of stomach ache by some rural communities in India and parts of Eastern Africa.
The leaves and seeds are also administered in cases of fever, and rheumatism since they possess anti-inflammatory, analgesic, and fever-lowering activity.
This green leafy vegetable is rich in beta-carotene for good eyesight; iron for healthy red blood cells; calcium for strong bones and teeth; and vitamin C for smooth, clear skin, strong immune cells, and fast wound-healing.
Similarly, experts have said that Corchorus olitorius leaf might also inspire future treatment for threatened miscarriage and preterm labour. This was attributable to its alkaloids content. Alkaloids are known to exert reversible smooth muscle relaxant activities.
Scientists in a study of Corchorus olitorius leaf found it significantly decreased the amplitudes of contractions in a dose-dependent manner such that the highest dose applied (666.67/ ìg/ml) achieved a 100 per cent inhibitory effect.
This 2019 online study in the Journal of Ethnopharmacology involved Daniel Orieke, Obioma Christopher Ohaeri, Ifeoma Irene Ijeh, Solomon Nnah Ijioma, all from the Michael Okpara University of Agriculture, Umudike, Abia State.
According to them, “If the results obtained in this study can be extrapolated to man, the Corchorus olitorius methanol leaf extract may be of value in the management of preterm labour and threatened abortion, diarrhoea and inflammations.”
In addition, researchers also suggested that individuals that experience acid reflux or heartburn drink ewedu juice to reduce the stomach acid that sometimes finds its way back through the throat.
In the study, researchers tested the antacid properties of jute leaves (ewedu) in male albino rats with a gastric ulcer over a two-week period that reduced the stomach acid production in a dose-dependent manner.
The 2015 study was entitled ‘Anti-Ulcerogenic and Gastric Antisecretory Effects of Corchorus olitorius Extract in Male Albino Rats’. It involved Bamidele V. Owoyele; W. Abdulmajeed; B. M. Adisa, O. O. Owolabi and Sabitiu A. Oyeleke, all from the University of Ilorin. It was in the Journal of Herbs, Spices & Medicinal Plants.
The study, which includes its pharmacological significance as an antacid, found that the extract of jute leaves and its root had 71.33 per cent antacid activity of a drug. It was in the International Journal of Pharmacy & Life Sciences.
Adapted from Tribune online.

By: Kevin Nengia

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RSG Plans Fresh Training For TBAs

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Plans are in the works by the authorities in the Rivers State Ministry of Health to conduct training for Traditional Birth Attendants(TBAs) in the State.
State Commissioner for Health, Dr. Adaeze Oreh gave the hint while chatting with newsmen recently in Port Harcourt.
She said the training has become crucial to school the TBAs on methods and measures to complement in maternal health care.
In her words,”  We are aware of of their roles, but we need to be confident that they can still play that role, especially the skills set needed to complement what government is doing.’’
Dr. Oreh explained that maternal and child care has evolved, hence, the TBAs need to be schooled,” we want them to scale up their skills, especially on high risk pregnancies.”
She continued, “ We want to make sure that our system mops up those high risk pregnancies, because we know that many of them carry out clandestine activities they are not helping us.”
Assuring of improved manpower in the State health sector, Dr. Oreh said the Governor Siminalayi Fubara administration has embarked on fresh recruitment exercise for health workers to meet current challenges.
She assured that once the recruitment exercise is completed, the various health centres and hospitals will be staffed with qualified manpower to provide efficient health services in the State.

Kevin Nengia

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Viral Hepatitis Claims 3,500 Lives Daily -WHO

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The World Health Organisation (WHO) has raised an alarm on viral hepatitis infection that claims 3,500 lives each day.
According to the World Health Organisation (WHO) 2024 Global Hepatitis Report, the number of lives lost due to the viral hepatitis is increasing.
The disease is the second leading infectious cause of death globally — with 1.3 million deaths per year, the same as tuberculosis, a top infectious killer.
The report, released at the World Hepatitis Summit revealed that despite better tools for diagnosis and treatment, and decreasing product prices, testing and treatment coverage rates have stalled.
It, however, said, reaching the WHO elimination goal by 2030 is still  achievable, if swift actions are taken now.
New data from 187 countries show that the estimated number of deaths from viral hepatitis increased from 1.1 million in 2019 to 1.3 million in 2022. Of these, 83percent were caused by hepatitis B, and 17percent by hepatitis C. Every day, there are 3,500 people dying globally due to hepatitis B and C infections.
“This report paints a troubling picture: despite progress globally in preventing hepatitis infections, deaths are rising because far too few people with hepatitis are being diagnosed and treated,” said WHO’s Director-General, Dr Tedros Adhanom Ghebreyesus.
He added, “WHO is committed to supporting countries to use all the tools at their disposal – at access prices – to save lives and turn this trend around.”
Updated WHO estimates indicate that 254 million people lived with hepatitis B and 50 million with hepatitis C in 2022. Half the burden of chronic hepatitis B and C infections is among people 30–54 years old, with 12percent among children under 18 years of age. Men account for 58percent of all cases.
New incidence estimates indicate a slight decrease compared to 2019, but the overall incidence of viral hepatitis remains high.
In 2022, there were 2.2 million new infections, down from 2.5 million in 2019.
These include 1.2 million new hepatitis B infections and nearly one million new hepatitis C infections. More than 6,000 people are getting newly infected with viral hepatitis each day.
The revised estimates are derived from enhanced data from national prevalence surveys. They also indicate that prevention measures such as immunisation and safe injections, along with the expansion of hepatitis C treatment, have contributed to reducing the incidence.

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How Dates Boost Fertility -Research

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Now, researchers in a study, suggest that date palm is an arsenal to fight infertility in couples. They found that 1-month consumption of date palm has a positive impact on the sexual function of infertile couples.
The study to investigate the effect of date palms on the sexual function of infertile couples  was in the 2022 edition of the BMC Research Notes.
In a double-blind, placebo-controlled clinical trial conducted on infertile women and their husbands who were referred to infertility clinics in Iran in 2019, researchers found sexual function in females (arousal, orgasm, lubrication, pain during intercourse, satisfaction) in the intervention group was significantly increased compared to females in the control group that had no date palm.
Infertility and infertility management affects different dimensions of a couple’s life. Sexual dysfunctions can appear in both partners and might provoke problems in every stage of sexual response. Infertility negatively affects the sexuality of infertile couples.
Numerous studies show that infertile women have lower sexual function than fertile women. Sexual satisfaction is strongly affected by the consequences of infertility such as reduced self-esteem, feelings of depression and anxiety, and failed sexual relationships.
The intervention group was given a palm date capsule and the control group was given a placebo. The starch powder was applied to prepare the placebo capsules.
Also, all areas of male sexual function (erectile function, orgasmic function, sexual desire, intercourse satisfaction and overall satisfaction) significantly increased in the intervention group compared to the control group.
Infertility is not only a medical problem but also affects all personal dimensions and social life of most infertile individuals. Infertile couples are more prone to psychological problems (anxiety, depression, and stress), which may result in marital distress, social dysfunction (stigma, social exclusion, and feelings of failure), and reduced quality of life.
Infertility and infertility management affects different dimensions of a couple’s life. Sexual dysfunctions can appear in both partners and might provoke problems in every stage of sexual response. Infertility negatively affects the sexuality of infertile couples.
Numerous studies show that infertile women have lower sexual function than fertile women. Sexual satisfaction is strongly affected by the consequences of infertility such as reduced self-esteem, feelings of depression and anxiety, and failed sexual relationships.
Dates palm is known to have come from what is now Iraq. In Nigeria, dry and soft date fruits are sold out for consumption. However, in the northern part, they are added to the locally brewed alcoholic beverage to help reduce the intoxicating power.
Dates are a good source of energy and vitamins and important elements such as phosphorus, iron, potassium and a significant amount of calcium. It is also rich in phenolic compounds possessing free radical scavenging and antioxidant activity.
Since ancient times, the date palm has been used in Greece, China and Egypt to treat infertility and increase sexual desire and fertility in females. There are few studies on the effect of date palms on male and female sexual function in human beings.
Besides, studies have shown that the various parts of its plant are widely used in traditional medicine for the treatment of various disorders which include memory disturbances, fever, inflammation, paralysis, loss of consciousness and nervous disorder.
Culled from Tribune online.

 

The researchers suggested that the improvement in male and female sexual function can be due to active ingredients and increased levels of sex hormones following the consumption of date palms since studies indicated that increasing sex hormones are effective in sexual function.

They, however, recommended more studies with a longer duration on the use of date palms on sex hormone levels in infertile couples.

Previously, a study revealed that using date palms in postmenopausal women for 1 month had a positive and significant impact on sexual desire and arousal.  Another suggested that using date palms had a positive impact on orgasm, satisfaction and lubrication in women and also reduced pain during intercourse in women.

In the laboratory, administering date palms to male rats and measuring their sexual behaviours, researchers showed that sexual behaviour parameters (number of ejaculations, number of intercourse) increased compared to the control group.

 

 

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