Ewedu Leaf Effective Against Ulcer – Study
If you’ve ever tried the delicious slimy soup called ‘ewedu’ in Yoruba or ‘rama’ in Hausa, you know how slimy it is. Now, this slimy soup can be used as an alternative therapy for the relief of stomach pain and ulcers.
Scientists in a study of Corchorus olitorius leaf, what is commonly called jute leaf, evaluated its effects on the passageway of the digestive system that leads from the mouth to the anus, on the diclofenac-induced gastric ulcers.
In the study, the researchers found that Corchorus trilocularis leaf extract has gastro-protective effects against diclofenac-induced gastric ulcers and attributed this effect to its inhibition of gastric acid secretion through multiple pathways in a dose-dependent fashion.
It prevents the digestive juice from attacking the wall of the stomach, preserves the mediation, increases the stomach’s pH and inhibits gastric acid secretion.
For the study, 36 Sprague dawley rats of either sex weighing 150-200 grams were randomly assigned into a normal control (distilled water), negative control (distilled water plus diclofenac sodium), treatment (200 and 400 mg/kg Corchorus trilocularis Linn plus diclofenac sodium), positive control group (omeprazole plus diclofenac sodium), or comparison group (400 mg/kg aqueous leaf extract of spinach).
In the study, Corchorus trilocularis extract significantly reduced the ulcer index and total acidity in comparison to the diclofenac group. The high dose extract also increased the alkaline nature of the stomach while also protecting the cells of the stomach. However, it did not significantly affect the volume of gastric secretions.
The researchers in the journal, Discovery Phytomedicine, declared “the findings in this study support the use of Corchorus trilocularis Linn by some communities in Eastern Africa for the relief of stomach pain and ulcers.
“In addition, it provides a novel finding that encourages its use as alternative therapy for those with pre-existing gastric ulcers, with the preferred consumption in its original state as a vegetable.”
One of the aggressive factors for gastric ulcer is the unending or high dose usage of Non-Steroidal Anti-Inflammatory Drugs (NSAIDs), which are among the most commonly used drugs worldwide. NSAIDs such as diclofenac usually used to relieve swelling and pain associated with conditions like gout, migraine and rheumatoid disease are commonly associated with the development of gastric ulcers.
Despite progress in the production of effective therapies against gastric ulcers, herbs and vegetables still provide an important source of alternative therapy in the prevention of ulcers.
Corchorus trilocularis, which is consumed as green leafy vegetables that are boiled and used as relish or potherb, is used for treatment of diseases of the abdominal organs and seeds for the treatment of stomach ache by some rural communities in India and parts of Eastern Africa.
The leaves and seeds are also administered in cases of fever, and rheumatism since they possess anti-inflammatory, analgesic, and fever-lowering activity.
This green leafy vegetable is rich in beta-carotene for good eyesight; iron for healthy red blood cells; calcium for strong bones and teeth; and vitamin C for smooth, clear skin, strong immune cells, and fast wound-healing.
Similarly, experts have said that Corchorus olitorius leaf might also inspire future treatment for threatened miscarriage and preterm labour. This was attributable to its alkaloids content. Alkaloids are known to exert reversible smooth muscle relaxant activities.
Scientists in a study of Corchorus olitorius leaf found it significantly decreased the amplitudes of contractions in a dose-dependent manner such that the highest dose applied (666.67/ ìg/ml) achieved a 100 per cent inhibitory effect.
This 2019 online study in the Journal of Ethnopharmacology involved Daniel Orieke, Obioma Christopher Ohaeri, Ifeoma Irene Ijeh, Solomon Nnah Ijioma, all from the Michael Okpara University of Agriculture, Umudike, Abia State.
According to them, “If the results obtained in this study can be extrapolated to man, the Corchorus olitorius methanol leaf extract may be of value in the management of preterm labour and threatened abortion, diarrhoea and inflammations.”
In addition, researchers also suggested that individuals that experience acid reflux or heartburn drink ewedu juice to reduce the stomach acid that sometimes finds its way back through the throat.
In the study, researchers tested the antacid properties of jute leaves (ewedu) in male albino rats with a gastric ulcer over a two-week period that reduced the stomach acid production in a dose-dependent manner.
The 2015 study was entitled ‘Anti-Ulcerogenic and Gastric Antisecretory Effects of Corchorus olitorius Extract in Male Albino Rats’. It involved Bamidele V. Owoyele; W. Abdulmajeed; B. M. Adisa, O. O. Owolabi and Sabitiu A. Oyeleke, all from the University of Ilorin. It was in the Journal of Herbs, Spices & Medicinal Plants.
The study, which includes its pharmacological significance as an antacid, found that the extract of jute leaves and its root had 71.33 per cent antacid activity of a drug. It was in the International Journal of Pharmacy & Life Sciences.
Adapted from Tribune online.
By: Kevin Nengia
Dental Association, Oyo Govt. Task Nigerians On Preventing Oral Diseases
Nigerian Dental Association (NDA) has urged Nigerians to take care of their oral health so as to reduce the burden of oral diseases.
NDA Chairman, Oyo State chapter, Dr Fechi Nkwocha, stated this at an event organised at St. Michael’s Primary School, Yemetu, Ibadan on Monday to commemorate the 2023 World Oral Health Day.
The News Agency of Nigeria (NAN) reports that the event was organised in collaboration with Oyo State Ministry of Health.
NAN also reports that the theme of this year’s World Oral Health Day is “Be proud of your mouth for a lifetime of smile.”
According to Nkwocha, the theme focuses on the importance of oral health at all stages of life.
“The standard of the World Dental Federation (FDI) is that children should possess 20 baby teeth (milk teeth) to be considered healthy, while healthy adults should have a total of 32 permanent teeth and zero tooth decay.
“Seniors must have a total of 20 natural teeth at the end of their lives to be considered healthy.
“To achieve this feat of optimal oral health for all, all hands must be on deck.
“Individuals, parents, teachers, caregivers, health care providers, policy makers, government and non-governmental organisations must collaborate to produce a healthy and productive population,” she said.
Nkwocha said that the burden of oral diseases, such as gum disease (gingivitis, bleeding gums), dental caries (tooth decay) and periodontitis had been high in Nigeria, leading to loss of teeth.
According to her, this is due to poor awareness of good oral health practices and the wrong perception of oral disease as having no serious consequence on general health.
“We want to remind our citizens that oral diseases have been known to cause severe disability and death.
“Oral diseases have been implicated in heart diseases, poor insulin and glucose control in patients with diabetes, low birth weight in pregnant women, to mention but a few.
“Treatment of advanced dental diseases are costly and time-consuming but thankfully, many of these oral diseases are preventable and easily treated in early stages with good oral health practices,” she said.
The NDA chairman decried limited access to oral health care facilities and services to Nigerians.
“With an estimated population of about 218 million as at 2022, Nigeria has an estimated dentist-to-population ratio of 1:54000, but worse in rural areas.
“This is a far cry from the recommended ratio of one dentist to 5,000 people, hence another reason for the poor oral health profile,” she said.
In his address, Oyo State Commissioner for Health, Dr Bode Ladipo, said that the celebration was an opportunity to create awareness on the importance of oral health.
Ladipo, who was represented by the Permanent Secretary in the ministry, Dr Olusoji Adeyanju, said that it was aimed at letting the public know that most oral health conditions were largely preventable and could be treated in their early stages without the associated morbidities.
“The WHO Global Oral Health Status Report (2022) estimated that oral diseases affect close to 3.5 billion people worldwide, with three out of four people affected in middle-income countries.
“This has made oral health a focus in the free health mission carried out across the 33 local government areas of the state on quarterly basis by the present administration’’.
“Free services are provided during this medical outreach and members of the community should take advantage of this quarterly activity,” he said.
Representative of the pupils of St. Michael’s Primary School and IMG Primary School, Taiwo Salami, appreciated kind gestures of the organisers of the free oral health programme.
Down SYNDROME -5000 Born Daily-UN
The United Nations has revealed that each year around five thousand children are born with Down Syndrome.
Every year World Down Syndrome Day is observed on March 21. The United Nation General Assembly declared March 21 World Down Syndrome Day in December 2011 and it began observing the day from 2012 onwards.
The 21st day of the third month has been selected as the designated date because the syndrome occurs due to the triplication of the 21st chromosome.
This year’s theme for World Down Syndrome Day 2023 is ‘With Us, Not For Us.’ The motive of this theme according to the UN is to ditch the old charity model and adopt a more human rights-based approach.
This theme it further explained encourages people to advocate for equality, as t seeks to view people with disabilities as having the right to be treated fairly, instead of viewing them as objects of charity, pity, and someone who needs to constantly rely on others for support.
Due to their condition, most of them may often face challenges in everyday life. This year’s theme urges people to change. Those with Down Syndrome must have the freedom to make their own choices and those supporting them must do things ‘with’ them, not ‘for’ them.
Down Syndrome is a genetic condition caused when anyone is born with an extra chromosome. People with Down Syndrome have some common features like small ears, a flat nose, eyes slanted up at the outer corner, protruding tongue, short neck, small hands and feet.
So far, Down Syndrome has no cure and is a lifelong condition. Nevertheless, there are treatments in place which, if received at the right time can help individuals live a meaningful life.
Those with Down Syndrome go through multiple emotional and physical challenges. Our society even today finds it difficult to accept them and even treat them differently. Every year, World Down Syndrome Day is observed on March 21 to raise awareness about the condition.
The life of those with Down Syndrome has not been easy. Besides hampered physical and mental development, the kind of ill-treatment and discrimination they are subjected to just worsens life for them. They are often face challenges while accessing basic rights like education, quality health services or the right to earn.
23 Rivers Indigenes Benefit From Free Eye Surgery
Over 23 persons have benefitted from a free eye Surgery organised by a non-governmental organisation, Steve Sandie foundation.
The beneficiaries were selected from the 23 Local Government Areas of Rivers State.
Sources however informed The Tide during the event that the surgery was bankrolled by a Rivers born philanthropist and politician who does not want his name mentioned.
Speaking at the programme, President, Steve Sandie Foundation, Mrs. Joyce Emmanuel said the programme was to help some indigent members of the society to solve their eyes problem.
She said beneficiaries were selected from the 23 local government areas of the state
Emmanuel said some of the critical cases will be referred while surgery will be performed on those that can be handled by the organisation at the centre.
She commended the donor for his concern on the plight of the less privileged.
According to her, the donor who does not want his name mentioned was so pathetic about giving sights to people.
Emmanuel said that the patients will be diagnosed and treated while serious cases will be referred for treatment at a higher health institutions
She said the organisation which was registered since 2008 has been involved in sensitising women on the values of caesarian operations.
Emmanuel said the group having discovered the need for caesarian section in some delivery cases has been talking to rural women on the need for them to go for it when necessary.
She however said most women who do not go for caesarian operations during delivery are doing so out of ignorance, as it is safe and cost effective.
Some of the beneficiaries of the free eye surgery including Obari Nwafor from Eleme thanked the group and the donor for the opportunity, stressing that the problem had taken him across to Calabar, Cross River State.
By: John Bibor
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