Alzheimer’s disease, named after the doctor who first described it (Alois Alzheimer), is a physical disease that affects the brain. Alzheimer’s disease also known as (AD) is the most common cause of dementia. The word dementia describes a set of signs that can include memory loss and difficulties with thinking, problem-solving or language. These signs occur when the brain is damaged by certain diseases, including Alzheimer’s disease.
According to the World Health Organization (WHO) Alzheimer’s disease is the most common cause of dementia and may contribute to 60- 70% of cases, During the course of the disease, proteins build up in the brain structures called ‘plaques’ and ‘tangles’. This leads to the loss of connections between nerve cells, and eventually to the death of nerve cells and loss of brain tissue. People with Alzheimer’s also have a shortage of some important chemicals in their brain. These chemical messengers help to transmit signals around the brain. When there is a shortage of them, the signals are not transmitted as effectively as they should be.
In 2010, there were between 21 and 35 million people worldwide with AD. It most often begins in people over 65 years of age.
It affects about 6% of people 65 years and older. In 2010, dementia resulted in about 486,000 death in UK alone, In developed countries AD is one of the most financially costly diseases and the disease is now thought to be the third leading cause of death in the U.S., right behind heart disease and cancer.
The cause of Alzheimer’s disease is poorly understood. About 70% of the risk is believed to be genetic with many genes usually involved. Other risk factors include a history of head injuries, depression or hypertension. The disease process is associated with plaques and tangles in the brain . A probable diagnosis is based on the history of the illness and cognitive testing with medical imaging and blood tests to rule out other possible causes.
However age is the greatest risk factor for Alzheimer’s. The disease mainly affects people over 65 above this age, a person’s risk of developing Alzheimer’s disease doubles approximately every five years. One in six people over 80 have dementia.
Many people fear that the disease may be passed down to them from a parent or grandparent. Scientists are investigating the genetic background to Alzheimer’s. There are a few families with a very clear inheritance of Alzheimer’s from one generation to the next. In such families the dementia tends to develop well before age 65. However, Alzheimer’s disease that is so strongly inherited is extremely rare. But then still there is no definite cause of Alzheimer’s Alzheimer’s has three stages with different symptoms. In the early stage of Alzheimerils . The first symptoms are often mistakenly attributed to ageing or stress people with AD, have increasing impairment of learning and memory eventually leads to a definitive diagnosis. In a small percentage, difficulties with language, executive functions, perception (agnosia), or execution of movements (apraxia) are more prominent than memory problems.AD does not affect all memory capacities equally. Older memories of the person’s life ( episodic memory), facts learned ( semantic memory), and implicit memory (the memory of the body on how to do things, such as using a fork to eat) are affected to a lesser degree than new facts or memories. Language problems are mainly characterized by a shrinking vocabulary and decreased word fluency , leading to a general impoverishment of oral and written language. In this stage, the person with Alzheimer’s is usually capable of communicating basic ideas adequately. While performing fine motor tasks such as writing, drawing or dressing, certain movement coordination and planning difficulties (apraxia) may be present, but they are commonly unnoticed. As the disease’ progresses, people with AD can often continue to perform many tasks independently, but may need assistance or supervision with the most cognitively demanding activities.
In the second stage Progressive deterioration eventually hinders independence, with subjects being unable to perform most common activities of daily living. Speech difficulties become evident due to an inability to recall vocabulary, which leads to frequent incorrect word substitutions (paraphasias ). Reading and writing skills are also progressively lost. Complex motor sequences become less coordinated as time passes and AD progresses, so the risk of falling increases. During this phase, memory problems worsen, and the person may fail to recognise close relatives. Long-term memory, which was previously intact, becomes impaired. Behavioral and neuropsychiatric changes become more prevalent. Common manifestations are wandering” and irritability leading to crying, outbursts of unpremeditated aggression, or resistance to caregiving. Sundowning can also appear. Approximately 30% of people with AD develop illusionary misidentifications and other delusional symptoms. Subjects also lose insight of their disease process and limitations (anosognosia). Urinary incontinence can develop. These symptoms create stress for relatives and careers, which can be reduced by moving the person from home care to other long-term care facilities.
During the final stages, the patient is completely dependent upon caregivers. Language is reduced to simple phrases or even single words, eventually leading to complete loss of speech. Despite the loss of verbal language abilities, people can often understand and return emotional signals. Although aggressiveness can still be present, extreme apathy and exhaustion are much more common symptoms. People with Alzheimer’s disease will ultimately not be able to perform even the simplest tasks independently; muscle mass and mobility deteriorate to the point where they are bedridden and unable to feed themselves. The cause of death is usually an external factor, such as infection of pressure ulcers or pneumonia, not the disease itself.
The National Institute of Neurological and Communicative Disorders and Stroke (NINCDS) and the Alzheimer’s Disease and Related Disorders Association (ADRDA, now known as the Alzheimer’s Association, say there is no cure for AIzaheimer’s. Since Alzheimer’s has no cure and it gradually renders people incapable of tending for their own needs, care giving essentially is the treatment and must be carefully managed over the course of the disease.During the early and moderate stages, modifications to the living environment and lifestyle can increase patient safety and reduce caretaker burden.
However, Lead researcher Dr, Shannon Macauley said: “Our results suggest diabetes, or other conditions that make it hard to control blood sugar levels, can have harmful effects on brain function and exacerbate neurological conditions such as Alzheimer’s disease. The link we have discovered could lead us to future treatment targets that reduce these effects.” A sensible diet; not getting fat; exercise; staying mentally active and engaged; don’t smoke; avoid sweets may help reduce the risk of contacting Alzheimer’s.”
As Alzheimer’s disease is highly prevalent, many notable people have developed it. Well- known examples are former United States President Ronald Reagan and Irish writer Iris Murdoch , both of whom were the subjects of scientific articles examining how their cognitive capacities deteriorated with the disease.
Other cases include the retired footballer Ferenc Puskas, the former Prime Ministers Harold Wilson (United Kingdom) and Adolfo Suarez ( Spain ), the actress Rita Hayworth, the actor Charlton Heston , the novelist Terry Pratchett ,the author Harnett Kane was stricken in his middle fifties and unable to write for the last seventeen years of his life, Indian politician George Fernandes , and the 2009 Nobel Prize in Physics recipient Charles K. Kao.
The global voice on dimentia declared September 2015 to mark the fourth global World Alzheimer’s Month, an international campaign to raise awareness and challenge the stigma. The theme for World Alzheimer’s Month 2015 is: Remember Me. They are encouraging people ‘all around the world to learn to spot the signs of dementia, but also not to forget about loved ones who are living with dementia, or those who may have passed away. The impact of September 0 s campaign is growing, but the stigmatisation and misinformation that surrounds dementia remains a global problem. At the beginning of September, ADI will launch the annual World Alzheimer Report.
Meanwhile, Alzheimer’s disease has proven a lot of changes on the lives of the human being and the numerous changes it cause on the humanity regarding its harmfulness. Therefore, people of various ages should give maximum support to efforts at curtailing the spread of the deadly disease Alzheimer’s. Remember it could be our grandparents, our parents or even ourselves. So it behoves us all to create awareness, spot the signs, love care, and support our elders because tomorrow might never come. All we have is today.
Tom is of Mass Communication Department, University of Maiduguri.
Jumping The Gun
It is a cheering news, to wit: “Nigeria Set To Begin Export Of Vehicle Parts, Heavy-Duty Metals” – ref. The Tide: Wednesday, Sept. 8, 2021. Zeetin, a Nigerian precision engineering company, whose Managing Director is Azibaola Robert, told Nigerians that his company signed an export Memorandum of Understanding with a Turkish-American Company, JMT Ltd, to export Zeetin’s products to other countries. Robert told us that: “this is the first time a Nigerian engineering and manufacturing company will start exporting heavy-duty metal products, spares to the international market”.
Any patriotic Nigerian would be glad to hear such news, rather than something saddening such as acts of banditry and brigandage. With the export of Zeetin vehicle parts and heavy-duty metals, “overall, Nigeria will be the ultimate beneficiary”. Hopefully, JMT Limited, while taking the responsibility of exporting and marketing Zeetin products, would have satisfied itself that the products are of international standards. It would not be enough for a precision engineering company to manufacture products, but there is also an additional responsibility of quality assurance.
Manufacturers Association of Nigeria (MAN) would obviously have satisfied itself that Zeetin products are of international standards. Therefore, credit must go to an indigenous Zeetin precision engineering company for being the first to export heavy-duty metal products and we hope that it would be a proud beginning; not Ajaokuta Steel!
Common stages involved in every project, including precision engineering works, would cover risk analysis, project design, implementation and then monitoring and evaluation. Purposes of monitoring and evaluation include getting factual and comprehensive feedback with regards to the performance of products sent out into the market. For manufacturing companies, lots of resources are spent on the feedback process, to ensure customer satisfaction and product sustainability. Complaints from customers and users are taken seriously so that corrections and improvements can be made.
At a seminar in the School of Oriental and African Studies, London, a long time ago, some useful facts emerged with regards to the common reactions of developing countries, to criticisms. Monitoring and evaluation process would obviously involve pointing out lapses calling for correction and improved strengthening. The emphasis was that criticism should not be seen as acts of aggression or hostility, but as opportunity for corrections and improvements. It takes maturity and a big heart to learn from scathing criticism.
With regards to product quality, developing countries, including Nigeria, have been known to have some lingering lapses, despite improved diligence. When there were talks in the recent times about Nigeria going to manufacture cars and aircraft, a former Nigerian diplomat swore that he, nor any of his grand children, would travel by such vehicle. Be it a joke or reality, his remark represents the attitude of many Nigerians towards local products. It is not always a question of ability or absence of it, but something else, quality included.
At the aforementioned seminar in the London school, there was a comment about “jumping the gun”, being a reference to an attitude of setting out long before the dawn. There is usually a difference between having an ability, and having the readiness to apply it, at the most appropriate time. Jumping the gun would mean embarking on a mission before one is ready enough to do so. Such haste may arise from vanity or some other weakness. It may not be wrong to take some risks or announce some breakthrough, but let it not be for “show” purposes.
In the management of development process, what is known as felt-need theory includes the practice of addressing needs and necessities according to the order of priority. Priority rating of a need would include the level of threat posed and the number of people involved. Commonsense understanding and assessment of a priority would mean “doing first thing first”. As First-Aid instructors would say. If threat to life is involved, then life-saving measures would be more appropriate priority than spending time in arguments while situation gets worse. You don’t go after rats while a house is on fire!
There was a time, a few years ago, when products packaged and exported from Nigeria were rejected abroad on the ground of not meeting international standards. Such products were not vehicle parts or heavy-duty metals. A major complaint about Nigerian-made products has always pointed towards “finishing and packaging”, which carry the tag of “poorly done”. There have been complaints that Nigerians rarely take serious pains to give a “good finishing” to what they produce. Products carry signatures of their origins and producers!
The endeavours and exploits of Zeetin have been used in this article as a means to examine what real progress means. That there are differences among individuals, nations, cultures and races, count as blessings and assets, rather than liabilities. Real progress shows in the development and advancement of what is indigenous to a people, rather than in copying and adopting foreign things, including engineering technology. Such progress begins with development of a right sense of beauty, not as a caricature but as an infallible signpost for knowing what exhibits harmony and creates joy. Beauty, Harmony, Joy!
People often strive in vain, and motivated by vanity, to copy and adopt what is not indigenous to their culture. Much time and resources are spent on wanting to follow the train of fashion, while efforts are rarely made to identify and develop indigenous talents. Obviously, every distinct group of people have unique endowments, peculiar to them, serving as their contribution to collective humanity. Harmony arises where differences in kind give their best to build up the whole through complementarily. Wherever one endeavour complements another, harmony arises.
Rather than be rooted in our native soil, culture and peculiar endowments, we copy and reproduce what is alien and borrowed from those we consider better. Such lifestyle of imitation is a major drawback for Nigeria. We progress better by being rooted in what we truly are and then build up from the grassroots; not by borrowing, copying or imitating what others had developed. From engineering works, to governance and health issues, there are indigenous and local content components that can give added values, if we Don’t Jump the Gun.
Dr Amirize is a retired lecturer from the Rivers State University, Port Harcourt.
Cursory Look At Nigeria’s Challenges
Insecurity and bad economy in Nigeria have reached alarming proportions rearing their ugly heads in various facets of our national life. Lives are lost on daily basis, population depleted, businesses in comatose, investment are nose-diving, multinationals closing shop and vacating the country, unemployment soaring and the populace in fear.
On May 29, 2015, General Muhammadu Buhari (rtd) was sworn in as President of Nigeria. The administration promised to urgently tackle several challenges that have hindered economic prosperity, sustainable security and overall national development in Nigeria. In terms of human resources, Nigeria is among the first 20 developed countries of the world. It is Africa’s largest oil-producing country. With a population of over 200 million, it is, no doubt, the largest market in Africa.
But the security and economic fortunes have been dwindling due to vagaries in the global price of crude oil. The country has been caught in-between affluence and affliction. Nigeria’s political leadership is a major factor why she has been reduced to a giant with clay feet. Buhari came to national limelight in 1983 when he became military Head of State after a successful coup d’état that overthrew civilian President Shehu Shagari on December 31, 1983. He ruled Nigeria from January 1984 until August 1985, before his regime was also toppled by another coup. His reign is ever remembered for a vigorous anti-corruption war, but tainted by human rights abuses.
Buhari contested in the presidential elections of 2003, 2007 and 2011, but lost to the Peoples Democratic Party (PDP) candidates. In the 2003, he was the presidential candidate of the All Nigeria Peoples Party (ANPP) and lost to incumbent President Olusegun Obasanjo. In 2007, he contested again on the ticket of the same party, but was beaten by PDP’s Umaru Yar’Adua who scored 26,638,063 against Buhari’s 6,605,299. In March 2010, the retired General left ANPP and formed the Congress for Progressive Change (CPC) contesting as its presidential candidate during the 2011 presidential poll, which he lost to President Goodluck Jonathan of PDP.
In that election, Buhari secured 12,214,853 votes against the President Goodluck Jonathan’s who secured 22,495,187. In 2014, the All Progressives Congress (APC) nominated Buhari to stand as its presidential candidate in the 2015 presidential election. The APC was merger of the All Progressives Grand Alliance (APGA), Action Congress of Nigeria (ACN), ANPP and CPC.
Buhari subsequently emerged victorious in the March 28, 2015 poll, defeating incumbent President Jonathan of PDP. He polled 15,416,221 votes against Jonathan’s 12,853,162 votes in an election that was keenly contested. On May 29, 2015, General Muhammadu Buhari was sworn in as president. Having ascended to the office he once occupied as a military officer, his administration was expected to urgently tackle several challenges that have bedeviled Nigeria over the last three decades. Insecurity, bad economy and corruption were the greatest challenges facing the new administrations since the return to democracy in 1999.
Traditional security threats such as violent conflicts, militancy, armed robbery and kidnapping have assumed worrisome dimensions in Nigeria. Evolving threats such as insurgency and terrorism have further complicated the situation. Outbreak of violent conflicts has become a major characteristic of insecurity in Nigeria. It is estimated that Nigeria has witnessed over 3,000 violent ethno-religious, communal and political conflicts of varying intensity and magnitude. Clashes between farmers and pastoralists have resulted in the death of about 4,732 persons between 1998 and 2014. The spate of violent crimes has become alarming.
In all of this the Presidency appears not to be doing enough, raising suspicions that Buhari is reluctant to take action since the herdsmen are mainly of his Fulani tribe. Even the swiftness with which Aso Rock Villa reacts to any condemnation of destructions caused by herders in the Middle Belt and southern parts of the country helps to fuel this suspicion.
Of course, the President’s insistence to recover gazetted grazing routes in the country lends further credence to the arguments of those who have maintained that he is deliberately keeping quiet and allowing his herder kinsmen to ride roughshod over every other section of the country. At best, all Buhari had ever ventured was that those who had complained about the destructions caused by open grazing should learn to tolerate the migrant herders and their cattle.
And on the economic front, the Buhari administration has a myriad of challenges to tackle which include but not limited to pervasive poverty, rising unemployment, epileptic power supply, fuel crisis and declining economy. Pervasive poverty and massive unemployment are serious economic challenges facing Nigeria. Both have maintained a rising trend over the years. Poverty rates remain high in Nigeria, particularly in rural areas. It is estimated that 101million out of Nigeria’s population of about 200 million live in extreme poverty.
And of the 99 million Nigerians suffering from extreme poverty, most are young people denied employment opportunities. However, as of 2015, the unemployment rate in Nigeria reached an all-time high of 20 percent with a youth unemployment rate as high as 50 per cent. These young Nigerians fell prey to recruitment by such groups as Boko Haram.
The problem of poverty and unemployment in Nigeria results from inconsistent policies, misappropriation of funds meant for empowerment schemes and increasing de-industrialisation and collapse of small businesses due to lack of venture capital and poor power supply.
Foreign industrial firms that once operated in this country have since relocated to other African countries like Ghana and South Africa which can boast of better operating environments. The oil multinationals that not only employed Nigerians and paid them very well have also relocated their key operations to offshore platforms in order to escape the increasingly restive Nigerian youth. This has led to staff downsizing across companies.
Achugo wrote from Eastern Polytechnic, Port Harcourt.
By: Godstime Achugo
Avoiding Brain-Drain In Medicare
The industrial action embarked upon by resident doctors in Nigeria has lasted for several weeks. A few months ago, the Nigerian Medical Association (NMA) was alleged to be demanding certain allowances, including that of COVID-19 inducement allowance.
The Federal Minister of Labour and Productivity, Dr Chris Ngige, the NMA and other stakeholders shifted grounds on the issues and came to a resolution which made them go back to work. This time around, the authorities concerned should also come together, sort out the problems concerning the medical practitioners so that the nation’s healthcare system is taken care of.
There is the fear that if they are not treated well, some of them may travel abroad for greener pastures. A situation where well-trained medical doctors will be leaving for other countries because the Nigerian system does not bother about them, should be avoided. Not just the doctors, nurses too should be taken care of as more of their services are needed in our public hospitals.
Although other professions are affected but that of medicare is more important as it deals with health. Health, they say, is wealth. A situation where a senior doctor may want to leave the country with his former students who have grown on the job for several years, to other countries because of the system in Nigeria calls for concern.
Those who may be wishing to leave should be patriotic. We are aware that many countries of the world like Canada, Australia, Germany, South Africa, to mention but a few, are seeking the services of Nigerian trained medical personnel. But it should be noted that their services are also needed in their country. As Nigerians, they need to be trusted to make some sacrifices as far as their services are concerned.
Some years back, when resident doctors embarked on strike in some of the states, there were threats of “No work, no pay”, their colleagues in other states voluntarily contributed and made funds available to them.
They should not be poor, but such calibre of persons should not be as it will be degrading. If they lack money as a result of non-payment of salaries and allowances, as punishment for industrial action, they have families and loved ones to cater for. Those who are leaving Nigeria for other climes may not be unpatriotic but need the kind of wages that are commensurate with the jobs they perform.
Researches have shown that brain-drain in Nigeria started in the early ’90s. One worrisome issue is that there are persons who at one time or the other have belonged to these associations before being at the helm of affairs. You discover that there will still be series of industrial action under their watch. So you begin to wonder whether these anomalies cannot be corrected as they are in charge.
Some persons have argued that Nigeria’s education system is poor. How come the nation’s medical graduates are good to the extent that other countries seek their services? I know that Nigeria has well-trained medical personnel who studied at home and can compete favourably at the international level.
Recently, I had an experience with some of our medical doctors, specifically in a female ward in one of our public hospitals; I was amazed at the way they were analysing health issues about women and prescribing the right drugs for the various ailments.
I began to wonder why anybody will say that we are nowhere. The truth is that we have qualified medical doctors. I think the problem is how to attend to their needs. If medical practitioners are asking for, let’s say, COVID-19 hazard allowance, they should be given so they don’t contract the virus.
The stress of a medical personnel attending to so many patients may not be easy, even at nights. When you visit the hospitals, one will not be in doubt that those groups of people deserve better working condition.
Nigerian medical doctors should be patriotic no matter their grievances, bearing in mind that “home is home”. The understanding between the indigenous medical personnel may not be the same as that of foreign medical team. Although there are some whose expertise are higher and left their countries of origin to render one assistance or the other in Nigeria.
There are also Nigerian trained medical doctors based overseas who, after taking a look at the situation in Nigeria, once in a while come home to render healthcare services. That’s a show of patriotism.
Education of a medical doctor in Nigeria is very expensive. In fact, securing admission to study medicine in the university does not come easy. So it’s like, “handle with care”.
While the Federal Government may need to look into the demands of resident doctors, NMA as a way of being patriotic, should shift ground during negotiation.
Brain-drain may not serve Nigeria well so they should not allow some of the best hands to leave. More so, you cannot tell whether they will return or not. All hands must be on deck because this is a period of pandemic.
Here in Rivers State, hospitals have been equipped with facilities of international standard which our medical personnel are competent to handle. The University of Port Harcourt Teaching Hospital (UPTH) and Rivers State University Teaching Hospital (RSUTH) have been equipped by both the federal and state governments. Spirited individuals and organisations have also donated facilities to those hospitals. The Military Hospital in Port Harcourt has also been equipped for anybody’s comfort.
In fact, the gigantic Mother and Child Hospital built by the Nyesom Wike administration is a testimony that healthcare system has been boosted. I think it is for the right medical personnel to man those facilities.
If our medical doctors are adequately taken care of, they will not leave the country for any reason. If you think any country is better than Nigeria, such place was not developed in a day. Whatever infrastructure you have overseas was developed over the years.
By: Eunice Choko-Kayode
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