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Hope Rises For Cancer Patients As Drug Passes First Test

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People with untreatable cancers now have hope if a new drug that will help their immune   attack their own tumours passes final test.
The drug according to reports is still at experimental stage and involves only 16 patients.
The new cancer breakthrough but has been called a “leap forward” and a “powerful” demonstration of the potential of such technology.
Each person had a treatment developed just for them, which targeted the specific weak spots in their tumour.
Reports says it’s too early to fully assess the therapy’s effectiveness and it is expensive and time-consuming.
The work focuses on a part of the immune system called T-cells, which patrol the body and inspect other cells for problems.
The drug uses proteins – called receptors – to effectively sniff out signs of infection or deviant cells that have become cancerous.
Cancers can be tricky for T-cells to spot. A virus is distinctly different to the human body, but cancers are more subtle because they are a corrupted version of our own cells.
The idea of the therapy is to boost levels of these cancer-spotting T-cells. It has to be tailored to each patient as each tumour is unique.
The researchers scoured patient’s blood for rare T-cells that already had receptors which could sniff out their cancer and after then harvested other T-cells that could not find the cancer and redesigned them.
Original receptors, which may find other problems or infections, were replaced with those from the cancer-searching T-cell.
With efficacy the drug help modified T-cells  then put back into the patient to seek out the tumour
Transforming T-cells into a form that can hunt cancer requires considerable genetic manipulation to both remove the genetic instructions for building their old receptors, and give them the instructions for the new ones.
The drug was made possible by tremendous advances in the gene-editing technology Crispr, which acts like a pair of molecular scissors – allowing scientists to easily manipulate DNA. The researchers who developed Crispr won which the Nobel Prize for Chemistry in 2020.

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Who Unveils Plans To Check HIV/AIDS Discrimination

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The World Health Organisation (WHO) at the 2024 International AIDS Conference, has released a technical brief titled, “Ensuring Quality Health care by reducing HIV-related Stigma and Discrimination.”
This technical brief is designed to assist health facility managers in providing quality, stigma-free services, and reinforcing the principle that every individual has the right to the highest attainable standard of physical and mental health.
The world health apex body observed that stigma and discrimination still remain significant barriers to accessing HIV-related care.
It noted that these barriers particularly affect key populations, hindering the uptake of and access to health services along the HIV services continuum.
There is a growing body of evidence demonstrating that effective interventions in the health sector can mitigate these issues by focusing on actionable drivers and facilitators of health-related stigma and its manifestations..
To ensure that people living with or affected by HIV can access and stay engaged in care, it is critical that health care workers have the skills to deliver quality stigma-free health services,” said Dr Meg Doherty, Director of WHO Global HIV, Hepatitis and STIs Programmes.
WHO’s technical brief emphasizes the necessity of integrating measures to improve the quality of health care and reduce stigma, ensuring everyone can access the services they need without fear of discrimination.”
The technical brief consolidates existing knowledge, outlines priority areas, describes key actions, and provides country examples to achieve quality, stigma-free health services. While the brief is primarily focused on the health facility level, it is also applicable to community service delivery models.

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Natural Recipe For Longer Life

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Natural Herbs
By Kelvin Nengia

Costa Rica is home to one of the world’s Blue Zones, where people live longer and healthier lives than average. The region of Cartago, called Llano Grande is known for its rich agriculture.
According to a cookbook author and cooking teacher a diet of “pura vida”, lifestyle is our secret to longevity.
Beans
Beans are a great source of protein, fiber, complex carbohydrates, prebiotics, vitamins and minerals. They have been linked to reduced risk of chronic diseases like heart disease and diabetes.
Black and red beans are the most popular, usually served as part of a casado (our traditional dish of rice, beans, veggies and protein) or as a soup consisting of beans and vegetables.
Chickpeas and lentils are popular there and can be used as a substitute for the traditional black beans.
Fresh Fruit and Vegetables
Fruit and vegetables in Costa Rica are generally eaten fresh, not out of a can or a freezer. We typically get our fruits and veggies from local markets called verdulerias.
Some of the most common ones in their diet are papaya, mango, banana, watermelon, pineapple and passion fruit, and they are either eaten on their own or made into drinks and juices.
They use a variety of vegetables in Costa Rican cooking, including potatoes, carrots, tomatoes, avocado, onion, beets, yucca and zucchini. Veggies are either eaten raw, in simple salads dressed with lime, or prepared as picadillo, chopped and boiled, occasionally with some animal protein mixed in for flavor.
Picadillo de chayote is probably another favorite. Chayote is a type of squash that is native to Central and South America, and not very common in the United States. It is green and crisp, and it tastes similar to a jicama.
Rice and Corn
Grains like rice and corn are present in diet Costa ricans but mainly as a complement to the beans and vegetables that we eat.
For instance, the tortillas are used to eat the picadillo popularly called “gallos.” Arroz con pollo is a traditional Costa Rican dish consisting of rice, a lot of chopped vegetables and different pieces of chicken.
This meal is a very popular at celebrations like birthdays, but it is also very commonly enjoyed day to day.
Coffee
In Costa Rican coffee is known for being high in antioxidants, which can help reduce inflammation. Sugary drinks are generally not a big part of the coffee-drinking culture.
Coffee here is enjoyed black or with a bit of milk. And as much as any other meal, a cup is best enjoyed slowly — we do take our time to drink.
It’s a favorite Costa Rican longevity recipe.
They eat rice and beans, either black or red, two to three times a day. For lunch this meal is called casado. For breakfast, it is called gallo pinto and consists of rice and beans mixed with onions, peppers, and cilantro, accompanied with corn tortillas and coffee.
Thanks to its combination of whole grains, protein, amino acids and antioxidants, longevity researcher and Blue Zones founder Dan Buettner considers gallo pinto to be the healthiest breakfast in the world. It is amazing how such a simple dish can be packed with so many health benefits.

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55 Million Battle Dementia as WHO PLANS To Check Disease

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The World Health Organisation(WHO) says currently, more than 55 million people have dementia worldwide with over 60%  living in low- and middle income countries.

It also revealed that every year, there are nearly 10 million new cases.

The revelation came as WHO Assembly endorsed a global action plan on the public health response to dementia 2017-2025.

The goal of the action plan is to improve the lives of people with dementia, their carers and families, while decreasing the impact of dementia on them as well as on communities and countries.

The action plan includes seven strategic action areas, including one on dementia risk reduction,as  there is no cure for dementia currently.

The body stressed that risk reduction for dementia remains critically important with potentially modifiable risk factors means that prevention of dementia is potentially possible by implementing a set of key interventions. This would, in turn, offer opportunities to influence future dementia incidence.

To this end, WHO released guidelines for risk reduction of cognitive decline and dementia in 2019. The guidelines provide health care providers as well as governments, policy-makers and other stakeholders with evidence-based recommendations on health  behaviours and interventions to delay or prevent cognitive decline and dementia.

Since the initial release of the guidelines, the field has evolved significantly, with more evidence now being available. In line with WHO standard procedure, the Department of Mental Health, Brain Health and Substance Use has started the process of updating the guidelines for risk reduction of cognitive decline and dementia with the advice of a Guideline Development Group (GDG).

Meanwhile, experts are proposing to join the GDG for updating the guidelines for risk reduction of cognitive decline and dementia based on their technical expertise, diverse perspectives, demographic background, lived experience and geographic representation

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