A researcher, Prof. Madubuike Ezeibe has called on the Federal Government to carry out a clinical trial of the drug he invented, Aluminum-Magnesium Silicate (AMS), for the treatment of HIV/AIDS.
Ezeibe, a professor of Veterinary Medicine, Michael Okpara University of Agriculture, Umudike (MOUAU), made the call in an interview with newsmen in Umuahia last Monday.
Clinical trial is a study that explores whether a medical strategy, treatment, or device is safe and effective for humans.
It shows which medical approaches that work best for certain illnesses or groups of people.
According to the don, he presented a paper on the potential of the drug as both antiviral and raw material, at a world conference on Ethnopharmacology in Chicago, United States, on May 2, 2016.
He said that more than one year after he invented and presented his findings at different international conferences, no authority anywhere in the world had disputed the research findings.
“I therefore appeal to the federal government to institute an inter-ministerial committee to carry out clinical trial of the drug in six centres across the country without further delay.
“The committee should comprise federal Ministries of Health, Education, Environment as well as Science and Technology, with, at least, 1000 sample patients from each state of the federation.
“Some of the findings of the research include that silicates have molecules that are 0.96 nanometer in size while HIV has molecules as big as 110 nanometer.
“The particles of AMS are positively and negatively charged, while HIV-infected cells are positively charged.
“The AMS are immune stimulants; one can use simple sugar (glucose) to transport charged molecules across the mucus membrane to the blood.
“Glucose helps to transport the drug to any part of the body, including ‘the sanctuary’, where other drugs cannot reach to attack the HIV-infected cells.
“So, if these findings are true and nobody has challenged the claims of the research, let the federal government set up an inter-ministerial committee to conduct clinical trial of the medicine,” he said.
Ezeibe expressed joy that the Vice Chancellor of MOUAU, Prof. Francis Otunta and the University Senate had investigated his claims and given their approvals.
He said that aside from the support from the university, the Abia Government also sponsored the publication of the book on AMS which, according to him, is now available for sale.
The researcher said that no fewer than 500 HIV cases within and outside Nigeria had been referred to him which he treated.
“All the HIV cases were referral from a medical doctor to the Medical Director of MOUAU. I have also handled referrals from different parts of African and Asian continents,” Ezeibe said.
Hypertension Treatment To Cut Down Death,WHO Assures
The World Health Organisation(WHO) yeasterday released its first report on the global impact of high blood pressure, assuring that with treatment improvement life expectancy may rise in 2050.
The dangerous effects of high blood pressure are highlighted in a new report by the World Health Organisation that identifies the condition as one of the world’s leading risk factors for death and disability.
WHO’s first report on the global impact of high blood pressure, also known as hypertension, offers recommendations on ways to combat the “silent killer.”
Hypertension, categorized as a blood pressure reading of 140/90 mmHg or higher, affects 1 in 3 adults worldwide, according to the report. It commonly leads to a number of other health problems including stroke, heart attack, heart failure and kidney damage.
Aspirin can help reduce risk of second heart attack, but study finds less than half of eligible adults take it
“Hypertension can be controlled effectively with simple, low-cost medication regimens, and yet only about one in five people with hypertension have controlled it,” Dr. Tedros Adhanom Ghebreyesus, the WHO director-general, said in a news release.
High-performing countries like Canada and South Korea have delivered comprehensive national hypertension treatment programs, according to WHO, and both nations have surpassed the 50 per cent mark for blood pressure control in adults with hypertension.
“An increase in the number of people effectively treated for hypertension to levels observed in high-performing countries could prevent 76 million deaths between 2023 and 2050”, the WHO said.
Neuropsychiatric Hospital Staff Dissociate Selves From Protest
Members of staff of the Federal Neuropsychiatric Hospital, Enugu have dissociated themselves from a recent protest staged at the hospital.
The protest was organised by a coalition of civil society organisations.
However, addressing journalists yesterday, the workers’ unions in the hospital said no member of staff took part in the said protest, but fingered touts who were hired to protest.
They include the Joint Health Sector Union, JOHESU, National Association of Nigeria Nurses and Midwives, NANNM, Association of Resident Doctors, ARD, and Medical and Dental Consultants Association of Nigeria, MDCAN, of the Federal Neuropsychiatric Hospital, Enugu.
Dr. Jane Nnabuchi of MDCAN, Dr Mbachu Ferguson of ARD, and Comrade Obinna Eze of JOHESU addressed the media on the issues.
The workers said touts were rather recruited by some persons to destabilise the hospital.
In a joint press statement issued by the workers, they debunked what they called “the stage-managed protest by a group of hired thugs that called themselves Civil Society Organisation (CSO) members, alleging that there is no peace in the hospital and that the workers are unhappy alongside other allegations levelled against the Medical Director, Prof. Monday Igwe.
“We hereby state categorically that the piece of information are not only false, but were made to mislead the general public and to cause confusion.”
The workers declared that: “there is no crisis in our hospital, Federal Neuropsychiatric Hospital, Enugu.
“That our hospital is peaceful and workers are happy with the administration of the Medical Director, Prof. Monday Igwe.
“That the stage-managed protest on 30th August, 2023 was done by thugs hired to discredit and destabilise the Medical Director and our hospital’s activity.
“We want to challenge anybody on that protest video circulating around to provide any proof of identity as staff of Federal Neuropsychiatric Hospital, Enugu or student of the School of Post Basic Psychiatric and Mental Health Nursing of our Hospital”.
“Ordinarily, we would have ignored the publication and the perpetrators of this dastardly and worthless act, but we are issuing a rejoinder to stop them from misleading the general public and most importantly, to put the information in the proper perspective.”
While making reference to a recent incident in the hospital, they called for an end to further harassment of the Medical Director.
“The situation created a scene and disrupted the activities of the hospital Community and would have escalated to an uglier scenario if not for the intervention of Enugu State Police Command.
“The members of Staff have been enjoying peace, infrastructural and human capacity development since the inception of Prof Monday Igwe’s leadership in 2019.
“We, the members of Joint Health Sector Union (JOHESU), National Association of Nigeria Nurses and Midwives (NANNM), Association of Resident Doctors (ARD), and Medical and Dental Consultants Association of Nigeria (MDCAN) of the Federal Neuropsychiatric Hospital, Enugu therefore, distance ourselves from and condemn that stage-managed protest of 30th August 2023 as well as the attempted abduction “arrest” of our Medical Director on Thursday, 14th September, 2023,” the workers further stated.
How Soft Drinks Affect Male Fertility -Research
DIET indeed has a significant influence on our health, a fact that cannot be denied. What we eat and drink greatly affect not only our physical health but also the ability to conceive. Consumption of soft drinks has a marked effect on fertility in both males and females.
Researchers, following a study in animals, even extrapolated that prolonged consumption of soft drinks is bad for male fertility. Its prolonged consumption has a stimulating effect on weight, with corresponding adverse effects on sperm production.
A global decline in total sperm counts, especially among men in western countries, continues to spark doomsday predictions. From chemicals in packaging to tight trousers, the decline in total sperm counts and quality has been attributed to multiple factors. High sugar intake as part of unhealthy modern lifestyles is also on the risk list.
It is well noticed in society today that people consume drinks without giving due consideration to the quantity taken, contents, the amount required by the body and the possible implications associated with excessive consumption.
The study, titled: ‘Adverse Effects of Excessive Soft Drinks Consumption on Male Fertility in Wistar Rat Models’ was in the March edition of the International Journal of Health and Medical Research.
Thirty-five male wistar rats were divided into five groups with the control groups administered with distilled water only and four other test groups administered with single dose (1.2ml) Coca-Cola, double dose (2.4ml) Coca-Cola (Cocacolax2), 0.6ml bullet drinks and 1.2ml sugar solution. Aside from the administered samples, food and water were regularly kept at their disposals.
Bullet drink is a caffeinated energy drink. The absence of regulatory supervision has resulted in over indulgence in the marketing of energy drinks. The effect of caffeine from natural coffee, tea, cocoa and foods that contain these ingredients has not been fully elucidated.
The rationale behind the use of albino wistar rats for human studies is that they are physiologically similar to humans and are small, sociable and easy to handle.
The weights of albino wistar rats before and after administration were measured to ascertain the effects of the test samples on the mean weight difference as well as their mean relative weight difference.
In addition, sperm parameters like the sperm count, motility, viability and morphology were taken to ascertain the effects of the test samples on fertility in the study which lasted 40 days.
After 40 days of administration of the test substances, there was an increase in the average body weights in all soft drink administered test groups, compared to how it was in the control group.
In relative terms, there were elevations in all relative body weights by 40.0 percent, 40.0 percent, 63.33 percent and 23.33 percent in single dose Coca Cola group, double dose group, bullet drink group and sugar solution group
respectively, compared to the control.
In the study, soft drinks administration insignificantly decreased the motility, count and viability with corresponding increase in percentage of sperm with abnormal morphology.
According to the researchers, the increase in mean weight difference and their corresponding relative weight differences noted among the test groups suggest the premise that all test substances generally and the bullet drink specifically, contain ingredients that cause voracious feeding resulting in increased obesity and marked weight gain.
They stated that the deleterious effects of the soft drinks on the sperm characteristics could be attributed to decreased and unfavourable sperm production activities in the testis.
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