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NAFDAC Orders Clinical Trial Of Chloroquine For COVID-19 Treatment
The National Agency for Food and Drug Administration and Control (NAFDAC) has ordered the manufacture of Chloroquine for an emergency stock and clinical trial for the treatment of Coronavirus (COVID-19).
The Director-General of NAFDAC, Prof. Mojisola Adeyeye, made this known in a statement, yesterday.
According to her, “In a very recent publication, Chloroquine was reported in a press briefing by the State Council of China, indicating that Chloroquine phosphate had demonstrated marked efficacy and acceptable safety in treating COVID-19 associated pneumonia in multi-centre clinical trials conducted in China.
“The study involved 10 hospitals in Wuhan, Jingzhou, Guangzhou, Beijing, Shanghai, Chongqing and Ningbo, and 100 patients. The investigators reported that Chloroquine phosphate is superior to the control in inhibiting pneumonia associated with COVID-19, and shortening the course of the disease.
“Chloroquine was discontinued in Nigeria many years ago for use as anti-malarial because of the resistance that the parasite developed against the drug. Therefore, sourcing the raw material – active pharmaceutical ingredient (API) – Chloroquine phosphate could be difficult.
“About four weeks ago, I approached a local manufacturing company (May and Baker), a member of Pharmaceutical Manufacturing Group of Manufacturing Association of Nigeria (PMGMAN), whose flagship product in the past was Chloroquine to make a batch of the drug for emergency stock. The company had NAFDAC approval for the production of the drug as anti-malarial many years ago before the discontinuation.
“The managing director expressed possible difficulty in getting the API due to the fact that the drug has been discontinued. He called shortly after that he was able to get the API and was asked to manufacture a batch for emergency stock just in case more people become exposed and infected with the virus. The batch has been manufactured and the company plans to make more batches if needed.
“As stated in my press briefing on March 20, 2020, NAFDAC is giving expedited provisional approvals for the manufacture of any commodities for preventing contracting the disease (sanitizers) and drug or medical device that could be used for the clinical trial testing and treatment of COVID-19 pandemic.
“The agency had reduced the 120 working days for approval to 10 days due to the crisis. The products should have been previously reported for clinical trial treatments in reputable scientific journals or technical literature as safe and effective.
“Other researchers in France, the US have used the drug for clinical trial treatment of COVID-19 and they reported effectiveness of the drug. Lagos State will be starting a clinical trial on Chloroquine to evaluate the effectiveness.
“Chloroquine works by increasing endosomal pH from the acidic environment required for virus/cell fusion, resulting in the inhibition of infection of SARS-CoV.
News
Don’t Panic, We’ll Protect Rivers Interest -Fubara
Rivers State Governor, Sir Siminalayi Fubara, has told the people of the State not to panic and be rest assured of the determination of his administration to protect lives and property of residents while improving the collective aspirations of the people.
Fubara gave the assurance when he addressed members of the Family Support Group, who were on solidarity visit to Government House in Port Harcourt on Wednesday to declare their unalloyed support to his administration.
Family Support Group is an assemblage of well-meaning Rivers youths, men and women drawn from the three Senatorial Districts and 23 local government areas, with the core aim of protecting, promoting and defending the interests of Rivers State.
The governor, who was represented by the Head of Rivers State Civil Service, Dr. George Nwaeke, said that the government is for the youths, women, men and every well-meaning Nigerian who wish the State well.
He assured that his administration would not disappoint their expectations, but would deliver good governance and quality services across all sectors.
Fubara said it was gratifying to see ebullient youths showing undying interest in government, and were also willing to defend their votes, and see him completing his tenure without interruption.
The governor explained that so many development projects had been completed and opened for public use with many others like the Port Harcourt Ring Road still actively ongoing.
He specifically noted the readiness of the administration to flag off construction of phase two of the real Trans-Kalabari Road from Port Harcourt through Tombia to other communities; and the Elele-Egbeda-Omoku Road.
“The whole land of Rivers State stands in affirmation that we won the election fairly, and deserve to serve out our full tenure. There is not going to be anything that will cut short the popular mandate that you all gave to this Administration.
“Just about within weeks of assuming office, His Excellency, Sir Siminalayi Fubara, flagged-off the Port Harcourt Ring Road project that will transverse six local governments. It will be completed within 36 months, but I think it will be completed before the time, because the progress of work we have seen is beyond what we were thinking.
“The Trans-Kalabari Road, very soon, the official main Trans-Kalabari Road will start, and will begin from Port Harcourt. That road, a lot of plans have been done, very soon, you will see contractors on site, and Rivers State will be opened.
“Just yesterday, you heard in the news also that the Governor has commenced the construction of the Elele-Egbeda-Omoku Road. That road was initially done with one lane, but now, he is going to dualise it. The Government has already awarded the contract”, he said.
Fubara emphasised that his administration is pro-youth and pro-human beings, and determined to maintain that level of empathy and inclusivity that offers succour to the people.
“I, therefore, want to thank you for the promise you have made, and I want you to remain unshakable. Keep your word of defending him at all times.
“When you hear anything outside, be bold, defend the Governor, and tell the people the things you know about him. Tell them what you know he has done to develop the State and the people”, he stated.
In his address, the President General of Family Support Group, Mr Henry Abraham, recalled that during the 2023 elections, they were encouraged to vote and defend their votes because the process was violence-free and credible.
“When we defend our votes, we will also defend the man we voted for. We are Family Support Group, Rivers State belongs to all of us. Rivers State is not a personal estate of one man, it’s for all Rivers people.
“Sir Siminalayi Fubara, stand firm. Family Support Group is with you. All the wards’ coordinators are with you. All the wards’ executives are with you. All the LGA coordinators are with you. All the officers of the National Executive Committee are with you. All our leaders are with you, and the PDP is with you,” he assured.
News
11 GDI Coordinators Declare Support For Fubara
The support base for the Rivers State Governor, Sir Siminalayi Fubara, swelled up on Wednesday when 11 Ward Coordinators of the Grassroots Development Initiative (GDI), in Ahoada-East Local Government Area of the State pledged unalloyed support and loyalty to his administration.
Ahoada East, which is the local government area of the Chief of Staff, Government House, Dr Edison Ehie, has a total of 13 electoral wards.
The 11 GDI Coordinators, who were in Government House, Port Harcourt on Wednesday on solidarity visit, said that they have now realised that they had been deceived and misled in the past few months, and decided to retrace their steps, and join the mass of Rivers people to defend and protect their votes and mandate freely given to Governor Fubara.
The coordinators, who were received by the Chief of Staff, Dr Edison Ehie, pledged to mobilise all their supporters and associates to give the State Government the necessary support and encouragement to deliver good governance and sustainable development to Rivers people.
They said that having watched the actions and policy direction of the governor, they have come to the realisation that sitting on the fence while detractors undermine the government was not in the best interest of the State.
The coordinators, who were accompanied by the former LGA Coordinator of GDI, Hon. Christian Abu, and Ahoada East LGA Chairman of the Peoples Democratic Party, Dr. Handsome Ekelechi Agile, said that they were resolute in their decision to join millions of well-meaning Rivers people who had solidified their membership of the SIMplified Movement to protect and defend the governor in the face of unwarranted attacks and campaign of calumny.
They said that with their movement to the SIMplified Family, the GDI structure in Ahoada East has completely collapsed.
They warned that anybody fighting the governor and the Chief of Staff would incur the wrath of the land.
In his remarks, Hon. Ehie assured the coordinators of the State government’s commitment to the wellbeing of all Rivers people and the consolidation of the gains of the infrastructure revolution of the administration.
He said that the Fubara-led government was operating an open door policy and running an inclusive administration, assuring that every Rivers man and woman will be touched positively by the actions, policies, and programmes of the government.
The GDI Coordinators included Chinwe Okorji representing Ward 1; Henry Uhor for Ward 2; Hon. Muzan Otuza of Ward 3; Hon. Elvis Ishikaku representing Ward 4; and Hon. Johnson Monday of Ward 5.
Others are Mr. Evidence Adi for Ward 6; Emmanuel Ochu of Ward 7; Hon. Fidelis Ikebuluwa representing Ward 8; Martins Odoi of Ward 9; Hon. Mackson Ekpeye representing Ward 10; Hon. Ambrose Ile for Ward 12.
With this development, the leadership of GDI at the Ward and LG levels have now dumped the group to join the Governor in efforts to transform the State.
News
Fubara Recommits To Human Capacity Building In Rivers
Rivers State Governor, Sir Siminalayi Fubara, has expressed the determination of his administration to build and strengthen the capacity of workers in the State’s Civil Service.
The governor said this during a meeting held behind closed doors in Government House, Port Harcourt, with the national leadership of Nigerian Institute of Management (NIM) Chartered, yesterday.
After the meeting, leader of the delegation and National President of NIM, Dr. Christiana Atako, told newsmen that Governor Fubara, a fellow of the Institute and astute manager, excited them with his plans on human capital development and other development initiatives.
Dr. Atako, who is also the Chairman of Council of NIM said, “In fact, he was talking so much about the civil service. I have told you that one of our strengths is to develop capacity of the workforce, and we told him that we are interested in the civil service of this State.
“We are interested in building capacity of the workforce because we believe that if you have the right workforce, you’ll be able to have successful system. And if you have a successful system, leadership will be very easy.”
She emphasised that, “And when we told him, he bought the idea. He said he was happy about that. He wants a situation where, apart from the infrastructure that he was putting in place, he also wants to build the capacity of the people.”
Atako stated that as an Institute, they were impressed with the giant strides of the leadership of the governor, the many infrastructural projects, both ongoing and completed, including the welfare packages for civil servants, particularly the Christmas bonus of N100, 000.00.
She pointed out the distinguishing attributes of a great and good leader, which include exhibiting empathy and motivating the workers to become more productive, which she said, were evident in the leadership shown by Governor Fubara.
Atako said they also informed the governor of their forthcoming annual national conference slated to hold in Port Harcourt, which is always used to discuss issues that are of interest to the growth and development of the country.
Those in the delegation were Registrar/Chief Executive of NIM, Mrs Taiwo Olusesi; former National Vice President, Dame Christie Toby; Council Members, Engr. Beniah Ojum; Prof. Sylva Opuala-Charles; Zonal Chairman and Chairman LOC NIM ANMC, Pastor Eyo Okpo-Ene; former National Treasurer, Chief Grant Orugbani; and Eze Ekpeye Logbo III, His Imperial Majesty, Kelvin N. Anugwo.
Others are former Deputy Speaker, Rivers State House of Assembly and Member LOC NIM ANMC, Rt. Hon. Marshall Stanley-Uwom; AGM, Hotel Presidential, Mr. Rex Yakpogoro; Member LOC NIM ANMC, Engr. Eze Egwurugwu; Sir Mike Elechi; Member LOC NIM ANMC, Dr. Kelechi Belinda Udeogu; Secretary, South South Zone and Secretary LOC NIM ANMC, Mr. Christian U. Abu; Emeritus Professor Simeon Chituru Achinehu.
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